American Cancer Hospital - Nigeria
Ikeduru Hospital Complex, KM 13 Owerri-Okigwe Road, Iho, Ikeduru, Imo State, Nigeria.
Tel:+234 (703) 4670640; +234 (814) 4102784; +234 (706) 4471111

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CHEMOTHERAPY

Breast Cancer:

Most Breast Cancers fall into four groups.

Treatment options (Chemotheraepy, Hormone therapy, Immunotherapy, Target therapy) will be based on these groups.

  • Group 1: - Luminal A – 40% of breast cancer: ER+VE, PR+VE, HER2-VE, LOW Ki67: (likely to benefit from hormone therapy and may also benefit from chemotherapy)
  • Group 2: - Luminal B – 20% of breast cancer: ER+VE, PR+VE, HER2+VE, HIGH Ki67: (likely to benefit from chemotherapy and may benefit from hormone therapy and treatment targeted to HER2)
  • Group 3: - HER2 ENRICHED – 10-15%: ER-VE, PR-VE, HER2+VE: (likely to benefit from chemotherapy and treatment targeted to HER2)
  • Group 4: - BASAL LIKE (TRIPLE NEGATIVE) 15-20%: ER-VE, PR-VE, HER2-VE: (No benefit from hormonal or anti HER2 but likely to benefit from selected chemotherapy)

NCCN Guidelines for the following:

A: Chemotherapy Regimens for Recurrent Metastatic Breast Cancer:

  • Regimens for ER- and/or PR-Positive Recurrent or Stage IV (M1) Disease1, HER2-Negative and Postmenopausal or Premenopausal Receiving Ovarian Ablation or Suppression
  • Regimens for ER- and/or PR-Positive Recurrent or Stage IV (M1) Disease1, HER2-Positive and Postmenopausal
  • Regimens For Recurrent or Stage IV (M1) Disease1, HER2-Negative
  • Regimens For Recurrent or Stage IV (M1) Disease1, HER2-Positive

B: Chemotherapy Regimens for Invasive Breast Cancer 

  • Adjuvant Endocrine Therapy: Hormone Receptor-Positive Disease: Premenopausal at diagnosis / Postmenopausal at diagnosis
  • Neoadjuvant/Adjuvant Chemotherapy, HER2-negative Disease / HER2-positive Disease

2. Cervical Cancer: Cervical Cancer

3. Urologic Cancers: Bladder, Prostate, Kidney Testes

4. Sarcoma: SOFT TISSUE SARCOMA TREATMENT REGIMENS 

 

Center of excellence for Cancer Care in Africa. Complete cancer treatment available in this center. American Cancer Teeatment and Research center is based in Imo state, in Nigeria, Africa.

2020

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American Cancer Hospital - Nigeria


Medical Disclaimer: The Contents of this site is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment.


 




Medical Disclaimer: The Contents of this site is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment.


 

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